Chat or rant, adult content, spam, insulting other members, show more. Harm to minors, violence or threats, harassment or privacy invasion, impersonation or misrepresentation, fraud or phishing, show more. Yahoo Answers. Where do B Cells mature? Where do B cells mature? I understand the germinal center's of Lymphatic nodes are the direct answer, but what organ as the T-cells mature in Thymus allow for the majority of maturation of blood cell?
Generation of lymphocytes in bone marrow and thymus - Immunobiology - NCBI Bookshelf
Without B-cells, your body would not be as effective at fighting off a number of common bacteria and viruses; and you would lack the long-lasting "memory antibody" function that is typical after recovering from an infection or after being immunized against a specific infectious invader. These blood-forming cells give rise to B-cells through a series of steps. The primary responsibility of B-cells involves the body's response to foreign invaders through what is known as humoral immunity. B-cells become "activated" when they encounter foreign antigens, as in foreign markers on the outside of bacteria cells during an infection. In response to such an infection, B-cells can differentiate into plasma cells—the body's antibody-producing factories. Plasma cells produce large proteins called immunoglobulins, or antibodies that attach to the surface of foreign agents.
Although mature lymphocytes all look pretty much alike, they are extraordinarily diverse in their functions. The most abundant lymphocytes are:. B lymphocytes often simply called B cells and T lymphocytes likewise called T cells. T-cells can only connect to virus antigens on the outside of infected cells.
A T cell is a type of lymphocyte which develops in the thymus gland and plays a central role in the immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor on the cell surface. These immune cells originate as precursor cells , derived from bone marrow ,  and develop into several distinct types of T cells once they have migrated in to the thymus gland - for which these cells are named. T cell differentiation continues even after they have left the thymus.